Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C152H252N44O42
- Molecular Weight: 3367.9 g/mol
- Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
Available Sizes
About
CJC-1295 without DAC is a synthetic analogue of Growth Hormone Releasing Hormone (GHRH) used to stimulate the pituitary gland to release Growth Hormone in a natural, pulsatile manner.
Mechanism of Action
CJC-1295 without DAC binds to GHRH receptors on the pituitary, mimicking the body's natural GHRH. Its modifications provide a half-life of about 30 minutes, creating a short, sharp pulse of GH release, closely resembling physiological patterns.
Key Benefits
- Stimulates natural Growth Hormone release
- Promotes a pulsatile GH secretion pattern
- Synergistic with GHRPs like Ipamorelin
- Relatively short half-life for controlled action
Clinical Research
Human studies have shown that a single bolus of Mod GRF 1-29 effectively stimulates pulsatile GH secretion, making it a valuable research tool for studying the GH axis. It is almost always used with a GHRP to maximize this effect.
Potential Side Effects
Side effects are generally mild and can include flushing, dizziness, or a head rush sensation shortly after administration, which typically subsides quickly.
Usage & Dosage
Typically administered via subcutaneous injection at a dosage of 100mcg, 1-3 times per day, often in conjunction with a GHRP like Ipamorelin. To maximize natural GH pulses, it is often administered before bed on an empty stomach.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).