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Epithalon
Epithalon
Epitalon, Epithalone

Key Characteristics

  • Category: Injectable Peptides
  • Purity: >99% Purity
  • Molecular Formula: C14H22N4O9
  • Molecular Weight: 390.3 g/mol
  • Sequence: Ala-Glu-Asp-Gly

Available Sizes

10mg

About

Epithalon is a synthetic tetrapeptide version of Epithalamin, a peptide naturally produced in the pineal gland. It is widely researched for its role in regulating telomerase and its potential anti-aging effects.

Mechanism of Action

Epithalon's primary mechanism is the activation of the enzyme telomerase, which helps to maintain and lengthen telomeres, the protective caps at the ends of chromosomes. This action helps to slow down cellular aging. It also regulates the circadian rhythm by influencing pineal gland function.

Key Benefits

  • Supports telomere lengthening and cellular longevity
  • Regulates circadian rhythms and sleep cycles
  • Promotes antioxidant defenses
  • May improve immune function

Clinical Research

Russian studies over several decades in both animal and human models have suggested that Epithalon can promote longevity, improve age-related decline in various physiological functions, and restore circadian rhythms.

Potential Side Effects

Epithalon is considered to have a very high safety profile, with no significant adverse effects reported in research.

Usage & Dosage

Administered via subcutaneous injection. Research protocols often involve cycles, such as 10-20 days of daily injections followed by a 4-6 month break. Daily dosages can range from 1-10mg.

Peptide Storage

Best Practices For Storing Peptides

To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.

For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.

Preventing Contamination

To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.

Storing Peptides In Solution

The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).

References

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