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IGF-1 LR3
IGF-1 LR3
Long-Arginine 3 IGF-1

Key Characteristics

  • Category: Injectable Peptides
  • Purity: >99% Purity
  • Molecular Formula: C400H625N111O115S9
  • Molecular Weight: 9211.5 g/mol

Available Sizes

1mg

About

IGF-1 LR3 is a modified, long-acting version of Insulin-like Growth Factor-1. It is a primary mediator of the anabolic effects of Growth Hormone and is a potent stimulator of muscle growth (hyperplasia).

Mechanism of Action

IGF-1 LR3 binds to the IGF-1 receptor on cells, initiating a cascade of intracellular signaling that promotes cell growth and proliferation, particularly in muscle cells. The "LR3" modification significantly increases its half-life by reducing its binding to IGF-binding proteins, allowing for more sustained anabolic activity.

Key Benefits

  • Potent stimulator of muscle hyperplasia (new muscle cell creation)
  • Enhances muscle protein synthesis
  • Aids in fat loss and nutrient partitioning
  • Supports rapid recovery and repair

Clinical Research

IGF-1 is extensively studied for its role in growth and development. Research on IGF-1 LR3 focuses on its enhanced potency and duration of action for applications in muscle wasting diseases and performance enhancement.

Potential Side Effects

The most significant potential side effect is hypoglycemia (low blood sugar), so it should not be administered without consuming carbohydrates. Other potential effects include fluid retention, headaches, and joint pain.

Usage & Dosage

Administered via subcutaneous or intramuscular injection. Research dosages typically range from 20mcg to 100mcg per day. It is often used post-workout to maximize its nutrient-shuttling and anabolic effects.

Peptide Storage

Best Practices For Storing Peptides

To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.

For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.

Preventing Contamination

To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.

Storing Peptides In Solution

The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).

References

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