Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C63H83N17O14
- Molecular Weight: 1302.4 g/mol
- Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Available Sizes
About
Kisspeptin is a critical neuropeptide that acts as a primary gatekeeper for the reproductive system, initiating the cascade of hormones responsible for sexual function and fertility.
Mechanism of Action
Kisspeptin binds to its receptor, GPR54, in the hypothalamus. This is the upstream signal that triggers the release of Gonadotropin-Releasing Hormone (GnRH), which in turn stimulates the pituitary to release LH and FSH, driving testosterone and estrogen production.
Key Benefits
- Potent stimulator of the HPTA axis
- Increases LH, FSH, and sex hormone production
- Crucial role in libido and reproductive function
- May influence mood and behavior
Clinical Research
Human studies have shown that Kisspeptin administration potently stimulates the reproductive axis and can enhance mood and brain activity associated with sexual arousal. It is a key focus of research in endocrinology and sexual medicine.
Potential Side Effects
Side effects are generally mild and can include flushing and nausea. As it powerfully stimulates the HPTA, its use requires careful consideration in research protocols.
Usage & Dosage
Administered via subcutaneous injection. Dosages and frequency vary widely depending on the research goal, from infrequent pulses to more regular administration to support the HPTA.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).