Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C101H152N28O22S2
- Molecular Weight: 2214.6 g/mol
- Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Available Sizes
About
MOTS-c is a novel peptide encoded within the mitochondrial DNA that plays a crucial role in metabolic regulation, insulin sensitivity, and cellular energy.
Mechanism of Action
MOTS-c functions as a signaling molecule that helps regulate metabolism. It enhances glucose uptake in muscle tissue, improves insulin sensitivity by activating the AMPK pathway, and promotes fatty acid oxidation, effectively mimicking some of the metabolic benefits of exercise.
Key Benefits
- Enhances insulin sensitivity and glucose utilization
- Promotes fatty acid oxidation (fat burning)
- Improves exercise capacity and endurance
- Supports mitochondrial health and cellular energy
Clinical Research
Animal studies have shown that MOTS-c can prevent age-related and diet-induced insulin resistance and obesity. It has also been shown to improve physical performance in older mice. Human trials are ongoing to explore its therapeutic potential.
Potential Side Effects
As a naturally occurring peptide, MOTS-c is expected to have a high safety profile. No significant adverse effects have been reported in current research.
Usage & Dosage
Administered via subcutaneous injection. Research protocols are still being established, but dosages in animal studies suggest human equivalent doses in the range of 5-10mg, administered several times per week.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).