Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C21H27N7O14P2
- Molecular Weight: 663.4 g/mol
Available Sizes
About
NAD+ is a critical coenzyme found in every cell in the body. It is essential for cellular energy production, DNA repair, and hundreds of metabolic processes. Levels decline significantly with age.
Mechanism of Action
NAD+ acts as an electron carrier in mitochondrial respiration, which is the primary process for generating ATP (cellular energy). It is also a crucial substrate for enzymes like sirtuins (which regulate aging) and PARPs (which repair DNA). Restoring NAD+ levels can improve mitochondrial function, enhance cellular repair, and support overall metabolic health.
Key Benefits
- Boosts cellular energy and metabolism
- Supports DNA repair and cellular health
- Activates sirtuins, the "longevity genes"
- May improve cognitive function and reduce inflammation
Clinical Research
Extensive research has linked declining NAD+ levels to age-related diseases. Studies on NAD+ precursors (like NMN and NR) and direct NAD+ administration have shown benefits in metabolic function, cardiovascular health, and neuroprotection in animal models. Human studies are rapidly expanding.
Potential Side Effects
When administered via IV, high doses can cause flushing, increased heart rate, and shortness of breath. Subcutaneous injections are generally better tolerated but may cause localized irritation.
Usage & Dosage
Can be administered via subcutaneous injection (50-100mg daily) or intravenous (IV) infusion (250-1000mg over several hours).
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).