Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C121H200N42O39 (peptide part)
- Molecular Weight: 2867.2 g/mol (peptide part)
- Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys-NH2
Available Sizes
About
PEG-MGF is a version of Mechano Growth Factor (a splice variant of IGF-1) that has been pegylated to increase its half-life, allowing its muscle-building and repair effects to last longer in the body.
Mechanism of Action
MGF stimulates myoblasts (muscle stem cells) proliferation and differentiation, which is crucial for muscle repair and growth. The pegylation process attaches polyethylene glycol (PEG) to the MGF molecule, protecting it from enzymatic degradation and extending its bioavailability from minutes to hours.
Key Benefits
- Promotes muscle repair and growth
- Increases muscle stem cell proliferation
- Extended half-life compared to standard MGF
- Supports recovery from resistance training
Clinical Research
Research in animal models has shown that MGF can induce rapid muscle hypertrophy and repair damaged muscle tissue. Pegylation is a well-established method to increase the stability and duration of action of peptides.
Potential Side Effects
Potential side effects can include localized irritation at the injection site. As with other growth factors, long-term effects of supraphysiological levels are a subject of ongoing research.
Usage & Dosage
Administered via subcutaneous or intramuscular injection, typically post-workout to target exercised muscles. Research dosages often range from 200-400mcg, 2-3 times per week.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).