Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C37H51N9O10S
- Molecular Weight: 813.9 g/mol
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Available Sizes
About
Semax is a neuropeptide developed in Russia, renowned for its potent nootropic and neuroprotective properties. It is an analogue of a fragment of adrenocorticotropic hormone (ACTH).
Mechanism of Action
Semax works by increasing the levels and expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). These proteins are crucial for neurogenesis, brain plasticity, and neuron survival. It also modulates neurotransmitter systems, including dopamine and serotonin.
Key Benefits
- Powerful nootropic for enhanced focus and memory
- Neuroprotective and neuro-regenerative effects
- Modulates dopamine and serotonin systems
- Can act as a stimulant without causing anxiety
Clinical Research
Semax is approved in Russia and Ukraine for various medical uses, including stroke recovery, cognitive disorders, and optic nerve disease. Its efficacy as a cognitive enhancer and neuro-restorative agent is supported by numerous Russian studies.
Potential Side Effects
Semax is considered very safe with a low incidence of side effects. Mild headache or nasal irritation (when used as a spray) can occur.
Usage & Dosage
Most commonly administered as a nasal spray to directly target the brain. It can also be given via subcutaneous injection. Dosages vary depending on the intended research purpose.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).