Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C221H366N72O67S
- Molecular Weight: 5135.8 g/mol
- Sequence: trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu
Available Sizes
About
Tesamorelin is a stabilized analogue of Growth Hormone Releasing Hormone (GHRH) specifically known for its ability to reduce visceral adipose tissue (VAT) and its potential nootropic effects.
Mechanism of Action
Like other GHRH analogues, Tesamorelin stimulates the pituitary to release Growth Hormone. Its unique modification makes it particularly effective at reducing visceral fat, the metabolically active fat stored around the organs. It also increases IGF-1 levels.
Key Benefits
- Proven to significantly reduce visceral adipose tissue (VAT)
- Stimulates natural Growth Hormone release
- May improve cognitive function in older adults
- Favorable effects on lipid profiles
Clinical Research
Tesamorelin is FDA-approved for the treatment of lipodystrophy (excess visceral fat) in HIV patients. Studies have also shown it can improve cognition in healthy older adults and those with mild cognitive impairment, and reduce liver fat.
Potential Side Effects
Common side effects include joint pain, fluid retention, and injection site reactions. It can also increase blood sugar levels, so it should be used with caution in individuals with diabetes or pre-diabetes.
Usage & Dosage
Administered via subcutaneous injection, typically once daily. The standard clinical dose is 2mg per day.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).