Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C129H215N33O55
- Molecular Weight: 3108.3 g/mol
- Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
Available Sizes
About
Thymosin Alpha-1 is a peptide produced by the thymus gland that is a potent modulator of the immune system, particularly in enhancing T-cell function.
Mechanism of Action
TA-1 works by restoring and modulating immune function. It promotes the maturation of T-cells, enhances the production of cytokines like IL-2 and IFN-gamma, and increases the expression of T-cell receptors, thereby augmenting the cell-mediated immune response against infections and malignancies.
Key Benefits
- Potent immune system modulator
- Enhances T-cell function and maturation
- Used as an adjunct therapy for various cancers and viral infections
- May improve vaccine response
Clinical Research
TA-1 (as Zadaxin) is approved in over 30 countries for the treatment of Hepatitis B and C and as an immune stimulant in cancer therapy. It has been extensively studied for its ability to bolster the immune system.
Potential Side Effects
Thymosin Alpha-1 is extremely well-tolerated, with virtually no side effects reported.
Usage & Dosage
Administered via subcutaneous injection. Dosages vary, but a common research protocol is 1.6mg administered 2-3 times per week.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).