Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C212H350N56O78S
- Molecular Weight: 4963.5 g/mol
- Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Available Sizes
About
Thymosin Beta 4 is a naturally occurring peptide that plays a crucial role in wound healing, tissue repair, and reducing inflammation. TB-500 is the synthetic version used in research.
Mechanism of Action
TB-500's primary function is to up-regulate actin, a protein critical for cell structure and motility. This action promotes the migration of cells to injury sites, accelerates the formation of new blood vessels (angiogenesis), and has potent anti-inflammatory effects, leading to faster and more efficient healing.
Key Benefits
- Accelerates wound and tissue healing
- Reduces inflammation
- Improves flexibility and reduces joint stiffness
- Supports cardiovascular and neural repair
Clinical Research
Extensive animal studies have shown TB-500 to be effective in accelerating healing in a wide range of tissues, including skin, muscle, heart, and eyes. It is a major focus of regenerative medicine research.
Potential Side Effects
TB-500 is very well tolerated, with no significant adverse effects commonly reported in research.
Usage & Dosage
Administered via subcutaneous injection. Research protocols often involve a 'loading phase' of 2-2.5mg twice weekly for 4-6 weeks, followed by a 'maintenance phase' of 2-2.5mg once or twice a month.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).